Get The Facts
Naloxone (Narcan) is a medication that swiftly reverses an opioid overdose. It can quickly restore normal breathing in someone whose breathing has slowed or stopped due to opioid poisoning or overdose. It has no impact on individuals without opioids in their system and is not a treatment for opioid use disorder. Immediate administration of naloxone is crucial, as every second counts.
Carrying naloxone is no different than carrying an epinephrine auto-injector (commonly known by the brand name EpiPen) for someone with allergies. It simply provides a rapid life saving response for those at a higher risk of overdose or in the event of an unsuspected poisoning.Naloxone is user-friendly and compact, making it easier to carry.Naloxone is available over-the-counter (OTC) in various locations, such as drug stores, grocery stores, your local health department/harm reduction services and online.
Save A Life
With the right tools, bystanders can act to prevent overdose deaths. Anyone can carry naloxone, give it to someone experiencing an overdose, and potentially save a life.
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An opioid overdose can occur when a person:

  • Overdoses on an illicit opioid drug, such as heroin or morphine
  • Overdoses on methadone
  • Accidentally takes an extra dose
  • Deliberately misuses a prescription opioid or opioid-based pain medication in a way that was not as prescribed by their physician
  • Mixes opioids with other prescriptions, alcohol, or over-the-counter medications. Overdoses can be fatal when mixing an opioid with anxiety treatment medications or derivatives of Benzodiazepine, such as Xanax or valium.
  • Uses medication prescribed for someone else. Children are particularly vulnerable to accidental overdoses if they take medication not intended for them.
How to Prevent Opioid Overdose
Opioid overdose can occur even with prescription opioid pain relievers and medications used in treating SUD such as methadone and buprenorphine. In addition, individuals using naltrexone for MOUD have a reduced tolerance to opioids, and therefore, using the same, or even lower doses of opioids used in the past, can cause life-threating consequences.
Always follow the instructions you receive with your medication. Ask your practitioner or pharmacist if you have questions or are unsure of how to take your medication. The following tips can help you or a loved one avoid opioid overdose: Take medicine as prescribed by your practitioner Do not take more medication or take it more often than instructed Never mix pain medicines with alcohol, sleeping pills, or illicit substances Never take anyone else medication Prevent children and pets from accidental ingestion by storing your medication out or reach. For more information, visit CDC’s Up and Away educational campaign. Dispose of unused medication safely. Talk to your MOUD practitioner for guidance, or for more information on the safe disposal of unused medications, visit FDA's disposal of unused medicines or DEA's drug disposal webpages.
How to Recognize Opioid Overdose
Opioid overdose is life-threatening and requires immediate emergency attention. Recognizing the signs of opioid overdose is essential to saving lives.
Call 911 immediately if a person exhibits ANY of the following symptoms:
Their face is extremely pale and/or feels clammy to the touchTheir body goes limpTheir fingernails or lips have a purple or blue colorThey start vomiting or making gurgling noisesThey cannot be awakened or are unable to speakTheir breathing or heartbeat slows or stops
How to Treat Opioid Overdose
Family members, caregivers, or the people who spend time with individuals using opioids need to know how to recognize the signs of an overdose and how to administer life-saving services until emergency medical help arrives. Individuals experiencing an opioid overdose will not be able to treat themselves. Naloxone was approved by the Food and Drug Administration (FDA) as the first over the counter medication to prevent opioid overdose. Check with your healthcare provider, pharmacy, community-based distribution programs, local public health organizations or the local health departments on how to obtain naloxone in your state.
If you suspect someone is experiencing an opioid overdose, take action immediately:
Call 911Begin CPR if the person has stopped breathing or if breathing is very weak (best performed by someone who has training)Treat the person with naloxone or nalmefene to reverse opioid overdose (if available)

ONEbox (TM)

Experience
The ONEbox (TM) is an emergency opioid overdose reversal kit designed to promote safety by assuring that individuals have life-saving, on-demand training when and where they need it.
Product Highlights
ONEbox Training Mode -Train yourself or your entire team on naloxone administration in minutes using the ONEbox training mode.
Find the Purple Box - The ONEbox delivers life-saving naloxone to the right location at the optimal time.
Emergency Response Mode -The ONEbox provides on-demand training during an emergency overdose situation to aid in by-stander intervention.
Setting up the ONEbox is easy and quick. Everything you need is already installed. JUST ADD NALOXONE!
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